Abstract. RICARDO, Luiz A. C.; TIAGO, Romualdo S. L. and FAVA, Antônio S.. Nasopharyngeal angiofibroma: review of literature. Rev. Bras. Otorrinolaringol. Nasal cavity, paranasal sinuses, nasopharynx - Nasopharyngeal angiofibroma. Juvenile angiofibroma (JNA) is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males.


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Clinically, however, it is angiofibroma nasofaringeo with painless, progressive unilateral nasal angiofibroma nasofaringeo being the common presenting symptom with or without epistaxis and rhinorrhea.

Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy and by using specialized imaging techniques such as arteriography, computer tomography and magnetic resonance imaging.

Histopathology reveals a fibrocellular stroma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern. A case report of JNA with rare intra-oral angiofibroma nasofaringeo in a year-old male patient angiofibroma nasofaringeo presented in the article.

JNA being an aggressive tumor may recur posttreatment.

Juvenile nasopharyngeal angiofibroma

Thus, early diagnosis, accurate staging, and angiofibroma nasofaringeo treatment are essential in the management of this lesion. It accounts for 0.

Adolescents and young adults between 14 and 25 years are affected, and there is a distinct male angiofibroma nasofaringeo. InFriedberg called it juvenile angiofibroma.

Angiofibroma nasofaríngeo juvenil

However, since a angiofibroma nasofaringeo majority of the cases do occur angiofibroma nasofaringeo 14 and 25 years of age, this term is retained.

The prevalence in males may be explained by high androgen receptor AR expression suggesting that JNA is androgen dependent.


Type I includes lesions fundamentally localized to the nasal cavity, paranasal sinus, nasopharynx, or pterygopalatine fossa. Type III angiofibroma nasofaringeo a calabash-like massive tumor lobe in the middle cranial fossa.

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Current debate angiofibroma nasofaringeo the hamartoma and vascular malformation theories. The histologic origin of JNA involves vascular endothelial cells or fibroblasts.

Angiofibroma nasofaríngeo juvenil - Wikipedia, la enciclopedia libre

Numerous angiofibroma nasofaringeo factors seem to be implicated in the pathogenesis of tumor. Angiofibroma nasofaringeo recent study of Schlauder et al suggests that the enzyme aromatase is responsible for local conversion of androgens to estrogens, which in turn relates to the role of estrogen receptors in tumor growth Currently it is believed that the tumor has its origin in the posterolateral wall of the nasal cavity, where the sphenoid process of angiofibroma nasofaringeo bone meets the horizontal lamina of the vomer and part of the pterygoid process of sphenoid bone.


This junction forms the upper margin of the sphenopalatine where lies the posterior portion of the middle turbinate. From your point of origin then begins its growth beneath the mucosa, extending initially to the posterior angiofibroma nasofaringeo cavity and nasopharynx 4.


Its blood supply is done by the internal maxillary artery, may also be branches of the ipsilateral internal carotid artery 4,6. The classic triad of epistaxis, unilateral nasal obstruction and a mass in the nasopharynx suggests the diagnosis of NAJ and is then supplemented by imaging tests 2,4,7, Computed tomography CTmagnetic resonance imaging MRI and endoscopic angiofibroma nasofaringeo are the choice to define the extent and location of the tumor, allowing thus staged.

Other methods such as hormone therapy, radiotherapy and chemotherapy treatment modalities are now used occasionally as complementary treatments 9,14,16,17, The surgical approach can be made through open, as the transpalatal, transmaxillary, rhinotomy lateral mid-facial degloving osteotomy and Le Fort type I 3,6,8,9,16, With the advent of minimally invasive techniques, endoscopic surgery has been used to treat NAJ in recent years 19ideal for tumors confined to the nasopharynx, nasal cavity, and sphenoid sinuses with minimal extension into the pterygopalatine fossa 2, 4,6,8,14, The first mention of an endoscopic resection date of Since then a number of cases were reported and all showed that endoscopic resection had a angiofibroma nasofaringeo morbidity for the early stages of disease 2.